Services

Automate eSource-to-EDC data flow

Nexa Trials eliminates duplicate data entry between eSource and EDC ? then supports your eSource platform and provides QC when you need a bridge during transition.

Clinical research coordinators reviewing digital study data and eSource workflows at a site workstation

Priority 1

Full data automation

Our primary focus: remove duplicate entry by automating structured data flow from eSource into your EDC.

Primary focus

Full Data Automation (eSource ? EDC)

Our automation engine removes the need for sites to re-enter data from eSource into the EDC. Structured data flows directly from the source system into the study database with automated mapping, protocol-aligned validations, and continuous oversight.

No duplicate entry ? data captured once in eSource
Faster EDC readiness ? no waiting for site transcription
Fewer queries ? errors caught before they reach the EDC
Real-time data in your study database across visits and forms

Nexa Bus? Data Integration

Nexa Bus? is the automation engine behind our eSource-to-EDC integrations ? a technology-agnostic layer that receives structured eSource exports and moves them reliably into downstream EDCs with AI-supported transformation and standardized mapping.

Compatible with leading eSource and EDC platforms
Consistent data flow without vendor lock-in
Centralized monitoring and quality oversight

Priority 2

eSource development & support

Strong automation needs strong eSource foundations ? we build, implement, and maintain the forms and workflows your studies depend on.

Secondary focus

eSource Development Overflow

Nexa Trials provides flexible, on-demand bandwidth for eSource development, allowing your team to scale quickly without delays. We take on overflow when internal resources are stretched, ensuring timelines stay on track.

Dedicated eSource developers and QA testers per study
Responsive, detail-oriented builds aligned with your standards
Flexible ramp up or down for new builds and amendments
Reliable coverage for mid-study updates

eSource Implementation

Implementing an advanced eSource platform requires clinical insight, operational understanding, and regulatory rigor. Nexa Trials ensures your implementation delivers value from day one.

Configuration matched to protocol, workflows, and site realities
Structured training and hands-on adoption support
Integration with EHRs, laboratory platforms, and EDC systems
Full compliance with 21 CFR Part 11 and electronic record regulations

Protocol-Driven eSource Design

We transform detailed study protocols into intuitive, visit-aligned eSource designs that sites can execute efficiently and consistently.

Clear conversion of protocol requirements into digital workflows
Precise field mapping, visit schedules, and metadata configuration
Advanced conditional logic to enforce protocol rules automatically
Designs optimized for usability and high-quality data capture

Custom Form Development

End-to-end custom form development in eSource, tailored to your study's unique requirements ? from requirements and design through deployment and updates.

Intelligent conditional logic, edit checks, and validations
Dynamic behavior and data reuse across visits
Alignment with CDISC/ODM standards and audit trails
Mobile-friendly layouts for busy site staff

Advanced Scripting & Customization

Our scripting expertise enables sophisticated, study-specific behavior within eCRFs ? improving accuracy and efficiency at the point of capture.

Dynamic field behavior based on subject data
Custom clinical validations and logical value relationships
Automatic calculations (BMI, dosing, time intervals)
Cross-form and cross-visit consistency checks

Back-Office Operations Support

Nexa Trials acts as an extension of your study team, providing dependable operational support throughout the trial lifecycle.

Study document generation and maintenance
Visit tracking, reconciliation, and operational oversight
Real-time issue resolution and ongoing study support
Sponsor and site communication assistance

Priority 3

Centralized data entry QC

For studies still using duplicate entry, QC provides a safety net while you transition to full automation.

Bridge service

Centralized Data Entry QC

We provide a dedicated QC layer for studies where sites perform duplicate data entry from eSource into the EDC. Our team reviews every entry across all sites to ensure accuracy, consistency, and alignment with CRF structure, protocol requirements, and data-management expectations.

Specialized QC analysts assigned to your study
Fast turnaround and clear discrepancy reporting
Consistent oversight across all visits and forms
Reduced site burden with early issue detection

Additional services

Data migration & cleansing

Data Entry, Cleansing & Migration

Reliable data services at every stage ? transforming legacy study data into clean, compliant, analysis-ready datasets.

Migration of legacy or external datasets into modern systems
Data cleansing, reconciliation, and structural alignment
Validation for high-quality, analysis-ready datasets

Engagement model

Automation first, then scale

We start by assessing your eSource-to-EDC duplicate entry workflows and automation potential. eSource development support and QC layer in as needed ? so you move toward zero duplicate entry at your pace.

Phase 01

Automation Assessment

Map eSource fields to EDC structures and identify the fastest path to eliminate duplicate entry.

Phase 02

eSource Development & Support

Strengthen eSource forms and workflows so automation has clean, protocol-aligned data to work with.

Phase 03

Centralized QC

Bridge hybrid workflows with QC oversight while automation rolls out across visits and sites.

Phase 04

Ongoing Support

Continuous automation monitoring, eSource updates, and QC as needed across amendments and new studies.

Pricing and engagement details are outlined in a mutually executed service agreement.

FAQ

Frequently asked questions

How long does it take to set up data automation for a study?

Most studies are ready in about 2 weeks from kickoff to go-live. Timeline can vary based on protocol complexity and how your eSource and EDC are configured.

What does it cost?

Every study is different ? contact us for a custom quote. Rest assured: our engagements are structured to cost less than your current duplicate-entry overhead.

Do you bring your own eSource tool?

No. We use what you already have ? your eSource platform, your CRF design, and your EDC. Nexa Bus integrates with your existing stack; we don't replace your tools.

Which EDC and eSource platforms do you support?

Nexa Bus is technology-agnostic. We integrate leading eSource platforms with EDC systems including Medidata Rave, Veeva, Oracle InForm, Castor, and others ? without locking you into a single vendor stack.

Can you help with a study that's already underway?

Yes. Many engagements start mid-study. We assess your current eSource-to-EDC workflows, map fields to your CRF, and roll out automation ? or layer in QC and eSource support while you transition.

What is Nexa Bus?

Nexa Bus is our integration engine that receives structured eSource exports and moves them reliably into your EDC with protocol-aligned mapping and validation ? eliminating the manual re-entry step between systems.

Will automation disrupt site workflows?

No. Sites continue capturing data in eSource as they do today. Automation removes the second step ? re-keying into the EDC ? so coordinators spend less time on admin without changing how they see patients.

We're not ready for full automation yet. Can you still help?

Absolutely. Our phased model lets you start with an automation assessment, add eSource development support as needed, and use centralized QC as a bridge for hybrid workflows until you're ready to scale.

Who do you work with?

We partner with clinical research sites, sponsors, and CROs across the United States, Europe, the GCC, and Pakistan ? from single-site studies to multi-site portfolios.

Is automated data compliant and audit-ready?

Yes. Automated flows are built with protocol-aligned mapping, validation rules, and audit trails from day one ? aligned with 21 CFR Part 11 and electronic record requirements for inspection readiness.

Discuss automation for your study

Tell us about your eSource and EDC setup ? we'll recommend the right starting point.